Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Visualization of prion-like transfer in Huntington's disease models.

Biochimica et biophysica acta. Molecular basis of disease - 1 Mar 2017

Jansen Anne H P, Batenburg Kevin L, Pecho-Vrieseling Eline, Reits Eric A

Abstract excerpt

Most neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington's disease are hallmarked by aggregate formation of disease-related proteins. In various of these diseases transfer of aggregation-prone proteins between neurons and between neurons and glial cells has been shown, thereby initiating aggregation in neighboring cells and so propagating the disease phenotype. Whereas this prion-like...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Huntingtin Protein
Share to Huntington Disease
Share to Neuroglia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neurons

Share to Prions

Share to Protein Aggregates

Share to Protein Aggregation, Pathological

Share to Protein Transport

Source

Identifiers

PMID: 28040507
DOI: 10.1016/j.bbadis.2016.12.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Visualization of prion-like transfer in Huntington's disease models.PMID 28040507Read ↗

Transfer of polyglutamine aggregates in neuronal cells occurs in tunneling nanotubesSemantic proximity Read ↗

Fate and propagation of endogenously formed Tau aggregates in neuronal cellsSemantic proximity Read ↗

Targeting prion-like protein spreading in neurodegenerative diseasesSemantic proximity Read ↗

Unconventional Secretion and Intercellular Transfer of Mutant HuntingtinSemantic proximity Read ↗

Protein transmission in neurodegenerative disease.Semantic proximity Read ↗

Extracellular Monomeric Tau Protein Is Sufficient to Initiate the Spread of Tau Protein PathologySemantic proximity Read ↗

Disease-related Huntingtin seeding activities in cerebrospinal fluids of Huntington's disease patients.Semantic proximity Read ↗

Novel human neuronal tau model exhibiting neurofibrillary tangles and transcellular propagation.Semantic proximity Read ↗

FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau fibersSemantic proximity Read ↗

An in vitro perspective on the molecular mechanisms underlying mutant huntingtin protein toxicity.Semantic proximity Read ↗

Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies.Semantic proximity Read ↗

Measurement of Tau Filament Fragmentation Provides Insights into Prion-like SpreadingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.