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Article

The RNA helicase DDX3 and its role in c-MYC driven germinal center-derived B-cell lymphoma

24 Mar 2023

Abstract excerpt

DDX3X is an RNA helicase with many functions in RNA metabolism such as mRNA translation, alternative pre-mRNA splicing and mRNA stability, but also plays a role as a regulator of transcription as well as in the Wnt/beta-catenin- and Nf-κB signaling pathways. The gene encoding DDX3X is located on the X-chromosome, but escapes X-inactivation. Hence females have two active copies and males only one. However, the Y...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37035206
DOI: 10.3389/fonc.2023.1148936

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The RNA helicase DDX3 and its role in c-MYC driven germinal center-derived B-cell lymphomaPMID 37035206Read ↗

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