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Article

pncA mutations are associated with slower sputum conversion during standard treatment of multidrug-resistant tuberculosis.

International journal of antimicrobial agents - 1 Feb 2017

Zheng Xubin, Ning Zhu, Drobniewski Francis, Yang Jingyong, Li Qun, Zhang Zhengdong, Hu Yi

Abstract excerpt

Despite the strong association between drug resistance and genetic mutations, the value of molecular diagnosis of drug resistance to guide the treatment of multidrug-resistant tuberculosis (MDR-TB) remains unclear. This is particularly relevant in resource-limited areas where it is difficult to perform drug susceptibility testing (DST). Here we investigated the association between drug susceptibility phenotypes...

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PMID: 28012685
DOI: 10.1016/j.ijantimicag.2016.10.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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