Article
Automated microraft platform to identify and collect non-adherent cells successfully gene-edited with CRISPR-Cas9.
Biosensors & bioelectronics - 15 May 2017
Attayek Peter J, Waugh Jennifer P, Hunsucker Sally A, Grayeski Philip J, Sims Christopher E, Armistead Paul M, Allbritton Nancy L
Abstract excerpt
Microraft arrays have been used to screen and then isolate adherent and non-adherent cells with very high efficiency and excellent viability; however, manual screening and isolation limits the throughput and utility of the technology. In this work, novel hardware and software were developed to automate the microraft array platform. The developed analysis software identified microrafts on the array with greater...
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