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Article

Dlx3 and GCM-1 functionally coordinate the regulation of placental growth factor in human trophoblast-derived cells.

Journal of cellular physiology - 1 Oct 2017

Li Sha, Roberson Mark S

Abstract excerpt

Placental growth factor (PGF) is abundantly expressed by trophoblast cells within human placentae and is important for trophoblast development and placental vascularization. Circulating maternal serum levels of PGF are dynamically upregulated across gestation in normal pregnancies, whereas low circulating levels and placental production of PGF have been implicated in the pathogenesis of preeclampsia and other...

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Share to Enhancer Elements, Genetic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27996093
DOI: 10.1002/jcp.25752

Genes

PGF
DLX3
GCM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Dlx3 and GCM-1 functionally coordinate the regulation of placental growth factor in human trophoblast-derived cells.PMID 27996093Read ↗

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GATA3 inhibits GCM1 activity and trophoblast cell invasionSemantic proximity Read ↗

Hypoxia and loss of <i>GCM1</i> expression prevents differentiation and contact inhibition in human trophoblast stem cellsSemantic proximity Read ↗

Hypoxia and loss of GCM1 expression prevent differentiation and contact inhibition in human trophoblast stem cellsSemantic proximity Read ↗

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