Article

VGLL1 contributes to both the transcriptome and epigenome of the developing trophoblast compartment

2025-04-29

Abstract excerpt

The trophectoderm (TE), the first lineage specified during mammalian development, initiates implantation and gives rise to placental trophoblasts. While animal models have elucidated key conserved signaling pathways involved in early TE specification, including BMP, WNT, and HIPPO, species-specific differences during early development emphasize the need for human-specific models. We previously identified VGLL1, a...

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Literature Corpus work: f17fa634-bea7-544a-aad8-44e612c10cab
DOI: 10.1101/2025.04.25.650693

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