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New insights into the regulation of placental growth factor gene expression by the transcription factors GCM1 and DLX3 in human placenta

9 May 2018

Abstract excerpt

Expression of placental growth factor (PGF) is closely associated with placental perfusion in early pregnancy. PGF is primarily expressed in placental trophoblasts, and its expression decreases in preeclampsia, associated with placental hypoxia. The transcription factors glial cells missing 1 (GCM1) and metal-regulatory transcription factor 1 (MTF1) have been implicated in the regulation of PGF gene expression...

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PMID: 29743241
DOI: 10.1074/jbc.ra117.001384

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New insights into the regulation of placental growth factor gene expression by the transcription factors GCM1 and DLX3 in human placentaPMID 29743241Read ↗

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