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Article

“Inflamm‐aging” influences immune cell survival factors in human bone marrow

20 Dec 2016

Abstract excerpt

The bone marrow (BM) plays a key role in the long‐term maintenance of immunological memory. However, the impact of aging on the production of survival factors for effector/memory T cells and plasma cells in the human BM has not been studied. We now show that the expression of molecules involved in the maintenance of immunological memory in the human BM changes with age. While IL‐15, which protects potentially...

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PMID: 27995612
DOI: 10.1002/eji.201646570

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