Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Advanced Age Alters Monocyte and Macrophage Responses.

Antioxidants & redox signaling - 20 Nov 2016

Albright Joslyn M, Dunn Robert C, Shults Jill A, Boe Devin M, Afshar Majid, Kovacs Elizabeth J

Abstract excerpt

SIGNIFICANCE: With the growing population of baby boomers, there is a great need to determine the effects of advanced age on the function of the immune system. Recent Advances: It is universally accepted that advanced age is associated with a chronic low-grade inflammatory state that is referred to as inflamm-aging, which alters the function of both immune and nonimmune cells. Mononuclear phagocytes play a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immunity, Innate
Share to Inflammation
Share to Adaptive Immunity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Macrophage Activation

Share to Macrophages

Share to Monocytes

Share to Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 27357201
DOI: 10.1089/ars.2016.6691
PMCID: PMC5107740

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Advanced Age Alters Monocyte and Macrophage Responses.PMID 27357201Read ↗

Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and function.Semantic proximity Read ↗

Advancements in Targeting Macrophage Senescence for Age-Associated ConditionsSemantic proximity Read ↗

Advanced Age Impairs Macrophage PolarizationSemantic proximity Read ↗

Human Monocyte Subsets Are Transcriptionally and Functionally Altered in Aging in Response to Pattern Recognition Receptor AgonistsSemantic proximity Read ↗

Senescent Polarization of Macrophages and Inflammatory Biomarkers in Cardiovascular DiseaseSemantic proximity Read ↗

Emerging Dynamics of Macrophage Cellular Senescence and Immunosenescence in Governing Organismal Aging and Disease: Concepts and OpportunitiesSemantic proximity Read ↗

Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during agingSemantic proximity Read ↗

Determinants of Resident Tissue Macrophage Identity and Function.Semantic proximity Read ↗

Tissue-resident macrophage inflammaging aggravates homeostasis dysregulation in age-related diseases.Semantic proximity Read ↗

Lung environment in healthy old age shapes the phenotype and CCR2-mediated recruitment of a subset of apoptotic, high-turnover alveolar macrophagesSemantic proximity Read ↗

Age-associated inflammatory monocytes are increased in menopausal females and reversed by Hormone Replacement TherapySemantic proximity Read ↗

Changes in macrophage phenotype as the immune response evolves.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.