Back to search

Article

The impact of body mass index on adaptive immune cells in the human bone marrow

2020-05-04

Abstract excerpt

<h4>Background: </h4> Obesity has been associated with chronic inflammation and oxidative stress. Both conditions play a determinant role in the pathogenesis of age-related diseases, such as immunosenescence. Adipose tissue can modulate the function of the immune system with the secretion of molecules influencing the phenotype of immune cells. The importance of the bone marrow (BM) in the maintenance of antigen-ex...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4fa29560-ae5f-5ad4-acd7-3ebbdd35a542
DOI
10.21203/rs.2.22852/v3
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The impact of body mass index on adaptive immune cells in the human bone marrowDOI 10.21203/rs.2.22852/v3
Several areas of overlap between obesity and aging indicate obesity as a biomarker of accelerated aging of human B cell function and antibody responsesSemantic proximity
Human bone marrow adipocytes display distinct immune regulatory propertiesSemantic proximity
B Cell Immunosenescence.Semantic proximity
T cell phenotypes associated with insulin resistance: Results from the Berlin Aging Study IISemantic proximity
Accumulation of γδ T cells in visceral fat with aging promotes chronic inflammationSemantic proximity
The impact of aging on memory T cell phenotype and function in the human bone marrowSemantic proximity
B Cells with a Senescent-Associated Secretory Phenotype Accumulate in the Adipose Tissue of Individuals with ObesitySemantic proximity
Exploring How Adipose Tissue, Obesity, and Gender Influence the Immune Response to Vaccines: A Comprehensive Narrative ReviewSemantic proximity
The effects of diet-induced obesity on B cell function.Semantic proximity
B Lymphocytes and Adipose Tissue Inflammation.Semantic proximity
Influence of Physical Activity and Nutrition on Obesity‐Related Immune FunctionSemantic proximity
Maternal obesity is associated with phenotypic alterations in fetal immune cells by single-cell mass cytometry.Semantic proximity
Select a neighboring publication to make it the new centre.