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Assessment of exonic polymorphism of IDH2, KRAS1, TP53, and BRAF2 using PCR-RFLP in hepatocellular carcinoma: a case-control study from Arunachal Pradesh and Sikkim.

Personalized medicine - 1 Apr 2026

Chauhan Chetan, Kumar Vishal, Narain Kanwar, Phukan Sanjib K, Kakoty Santanu, Tawsik Sopai, Bhutia Chewang D, Devi Kangjam Rekha

Abstract excerpt

INTRODUCTION: The primary liver cancer of greatest concern is hepatocellular carcinoma (HCC). It covers almost 80% of liver cancer in the global population, and in the next two decades, it is expected to increase by 15%. The biomarker-based study has therapeutic potential to enhance therapy responses for HCC. AIM: Thus, the present study investigates genetic polymorphisms in key genes from HCC patients in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41978346
DOI: 10.1080/17410541.2026.2657976

Genes

IDH2
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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