Article
Genetic variants of SOS2, MAP2K1 and RASGRF2 in the RAS pathway genes predict survival of HBV-related hepatocellular carcinoma patients.
Archives of toxicology - 1 Jun 2023
Lin Qiuling, Qiu Moqin, Wei Xueyan, Xiang Zhouyun, Zhou Zihan, Ji Iiangyan, Liang Xiumei, Zhou Xianguo, Wen Qiuping, Liu Yingchun, Yu Hongping
Abstract excerpt
The RAS pathway participates in the cascade of proliferation and cell division process, and the activated RAS pathway can lead to tumorigenesis including hepatocellular carcinoma (HCC). However, few studies have explored the effects of genetic variants in the RAS pathway-related genes on the survival of patients with HBV-related HCC. In the present study, we assessed the associations between 11,658...
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