Alcohol Consumption and Cigarette Smoking are Important Modifiers of the Association Between Acute Pancreatitis and the PRSS1-PRSS2 Locus in Men.

doi:10.1097/MPA.0000000000000729

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Alcohol Consumption and Cigarette Smoking are Important Modifiers of the Association Between Acute Pancreatitis and the PRSS1-PRSS2 Locus in Men.

Pancreas - 1 Feb 2017

Polonikov Alexey V, Samgina Tatyana A, Nazarenko Petr M, Bushueva Olga Y, Ivanov Vladimir P

Abstract excerpt

OBJECTIVES: The present study was designed to investigate whether the susceptibility to acute pancreatitis (AP) attributable to polymorphism rs10273639 at the PRSS1-PRSS2 locus is dependent on alcohol consumption and cigarette smoking. METHODS: A total of 603 unrelated Russian individuals including 304 patients with physician-diagnosed AP and 299 sex- and age-matched healthy controls have been recruited for the...

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PMID: 27846138
DOI: 10.1097/MPA.0000000000000729

Genes

PRSS1
PRSS2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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