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Transcriptomic evidence for modulation of host inflammatory responses during febrile Plasmodium falciparum malaria

10 Aug 2016

Abstract excerpt

Identifying molecular predictors and mechanisms of malaria disease is important for understanding how Plasmodium falciparum malaria is controlled. Transcriptomic studies in humans have so far been limited to retrospective analysis of blood samples from clinical cases. In this prospective, proof-of-principle study, we compared whole-blood RNA-seq profiles at pre-and post-infection time points from Malian adults...

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PMID: 27506615
DOI: 10.1038/srep31291

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