Article
Warfarin genotyping with hybridization-induced aggregation on a poly(ethylene terephthalate) microdevice.
The Analyst - 16 Jan 2017
Sloane Hillary S, Carter Morgan B, Cecil Alexa E C, Le Roux Delphine, Mills Daniel L, Landers James P
Abstract excerpt
Warfarin, a commonly prescribed oral anticoagulant, is burdened by a narrow therapeutic index and high inter-individual variability in response, making it the second leading cause of drug-related emergency room visits. Since genetic factors contribute significantly to warfarin sensitivity, a genotype-guided dosing strategy may reduce the occurrence of adverse events. While numerous methods have been demonstrated...
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