Article
Warfarin genotyping in a single PCR reaction for microchip electrophoresis.
Clinical chemistry - 1 Apr 2012
Poe Brian L, Haverstick Doris M, Landers James P
Abstract excerpt
BACKGROUND: Warfarin is the most commonly prescribed oral anticoagulant medication but also is the second leading cause of emergency room visits for adverse drug reactions. Genetic testing for warfarin sensitivity may reduce hospitalization rates, but prospective genotyping is impeded in part by the turnaround time and costs of genotyping. Microfluidics-based assays can reduce reagent consumption and analysis...
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