Article
Comparison of performance of three commercial platforms for warfarin sensitivity genotyping.
Clinica chimica acta; international journal of clinical chemistry - 1 Aug 2009
Babic Nikolina, Haverfield Eden V, Burrus Julie A, Lozada Anthony, Das Soma, Yeo Kiang-Teck J
Abstract excerpt
BACKGROUND: We performed a 3-way comparison on the Osmetech eSensor, AutoGenomics INFINITI, and a real-time PCR method (Paragonx reagents/Stratagene RT-PCR platform) for their FDA-cleared warfarin panels, and additional polymorphisms (CYP2C9*5, *6, and 11 and extended VKORC1 panels) where available. METHODS: One hundred de-identified DNA samples were used in this IRB-approved study. Accuracy was determined by...
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