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Article

Polymorphisms of Genes Encoding Multidrug Resistance Proteins as a Predictive Factor for Second-Line Docetaxel Therapy in Advanced Non-small Cell Lung Cancer.

Pathology oncology research : POR - 1 Jul 2017

Szczyrek Michał, Mlak Radosław, Krawczyk Paweł, Wojas-Krawczyk Kamila, Powrózek Tomasz, Szudy-Szczyrek Aneta, Zwolak Agnieszka, Daniluk Jadwiga, Milanowski Janusz

Abstract excerpt

Multidrug resistance (MDR) remains a substantial problem in chemotherapy. The purpose of the study was to investigate potential factors, including MDR genes polymorphisms, that could be used in qualification for second-line docetaxel therapy in non-small cell lung cancer (NSCLC) patients after failure of platinum based chemotherapy. Study group comprised of 58 Caucasian subjects. Evaluation of Single Nucleotide...

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Source

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Identifiers

PMID: 27988838
DOI: 10.1007/s12253-016-0156-4
PMCID: PMC5487877

Genes

ABCC2
ABCB1
TUBB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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