Article
ABCB1 polymorphism as prognostic factor in breast cancer patients treated with docetaxel and doxorubicin neoadjuvant chemotherapy.
Cancer science - 1 Jan 2015
Kim Hee-Jun, Im Seock-Ah, Keam Bhumsuk, Ham Hye Seon, Lee Kyung Hun, Kim Tae Yong, Kim Yu Jung, Oh Do-Youn, Kim Jee Hyun, Han Wonshik, Jang In-Jin, Kim Tae-You, Park In Ae, Noh Dong Young
Abstract excerpt
Expression of the adenosine triphosphate-binding cassette B1 (ABCB1) transporter and P-glycoprotein are associated with resistance to anticancer drugs. The purpose of this study was to investigate the role of single nucleotide polymorphism in the ABCB1 and CYP3A genes in breast cancer patients who were treated with neoadjuvant chemotherapy. Stage II/III breast cancer patients were treated with three cycles of...
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