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Article

Influence of ABCB1 polymorphisms and docetaxel pharmacokinetics on pathological response to neoadjuvant chemotherapy in breast cancer patients.

Breast cancer research and treatment - 1 Jun 2013

Lévy Pierre, Gligorov Joseph, Antoine Martine, Rezai Keyvan, Lévy Eric, Selle Frédéric, Saintigny Pierre, Lokiec François, Avenin Danielle, Beerblock Karine, Lotz Jean-Pierre, Bernaudin Jean-François, Fajac Anne

Abstract excerpt

We have previously reported an association between ABCB1 C3435T polymorphism and docetaxel pharmacokinetics in breast cancer patients. We therefore investigated whether these parameters could account for variations in pathological response. Five ABCB1 polymorphisms including C3435T polymorphism were analyzed in breast cancer patients receiving neoadjuvant chemotherapy with doxorubicin and docetaxel (n = 101)....

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Source

Identifiers

PMID: 23666532
DOI: 10.1007/s10549-013-2545-7

Genes

ABCB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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