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Article

Association between gene polymorphism and adverse effects in cancer patients receiving docetaxel treatment: a meta-analysis.

Cancer chemotherapy and pharmacology - 1 Feb 2022

Yan Mingrui, Fan Xiaoyu, Si Hongyanhua, Wang Xiaoyu, Wang Zhe, Wang Zhen, Lv Xin, Yin Hang, Jia Yanyan, Jiang Lili, Xia Yangliu, Liu Yong

Abstract excerpt

PURPOSE: Large interindividual variability in the pharmacokinetic properties of docetaxel has been reported, with the clearance of docetaxel varying nearly six fold, in which pharmacogenetics of docetaxel may play an essential role in addition to physiological factors. The association between the gene polymorphism and risk of adverse clinical effects in docetaxel treated patients has been examined in several...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34988655
DOI: 10.1007/s00280-021-04374-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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