Article
Quantitative systems pharmacology: a promising approach for translational pharmacology.
Drug discovery today. Technologies - 1 Jan 2000
Gadkar K, Kirouac D, Parrott N, Ramanujan S
Abstract excerpt
Biopharmaceutical companies have increasingly been exploring Quantitative Systems Pharmacology (QSP) as a potential avenue to address current challenges in drug development. In this paper, we discuss the application of QSP modeling approaches to address challenges in the translational of preclinical findings to the clinic, a high risk area of drug development. Three cases have been highlighted with QSP models...
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