Mechanistic systems modeling to guide drug discovery and development.

Abstract excerpt

A crucial question that must be addressed in the drug development process is whether the proposed therapeutic target will yield the desired effect in the clinical population. Pharmaceutical and biotechnology companies place a large investment on research and development, long before confirmatory data are available from human trials. Basic science has greatly expanded the computable knowledge of disease processes,...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Drug Discovery
• Share to Models, Biological
• Share to Phenotype