Systems Pharmacology in Small Molecular Drug Discovery.

Abstract excerpt

Drug discovery is a risky, costly and time-consuming process depending on multidisciplinary methods to create safe and effective medicines. Although considerable progress has been made by high-throughput screening methods in drug design, the cost of developing contemporary approved drugs did not match that in the past decade. The major reason is the late-stage clinical failures in Phases II and III because of the...

Topics

• Computational Biology
• Computer Simulation
• Drug Design
• Drug Discovery
• Humans
• Ligands
• Molecular Targeted Therapy
• Neural Networks, Computer
• Pharmacology
• Phenotype
• Quantitative Structure-Activity Relationship
• Small Molecule Libraries
• Systems Biology