Article
Systems Pharmacology in Small Molecular Drug Discovery.
International journal of molecular sciences - 18 Feb 2016
Zhou Wei, Wang Yonghua, Lu Aiping, Zhang Ge
Abstract excerpt
Drug discovery is a risky, costly and time-consuming process depending on multidisciplinary methods to create safe and effective medicines. Although considerable progress has been made by high-throughput screening methods in drug design, the cost of developing contemporary approved drugs did not match that in the past decade. The major reason is the late-stage clinical failures in Phases II and III because of the...
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