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A Quantitative Systems Pharmacology Model of T Cell Engager Applied to Solid Tumor

12 Jun 2020

Abstract excerpt

Cancer immunotherapy has recently drawn remarkable attention as promising results in the clinic have shown its ability to improve the overall survival, and T cells are considered to be one of the primary effectors for cancer immunotherapy. Enhanced and restored T cell tumoricidal activity has shown great potential for killing cancer cells. Bispecific T cell engagers (TCEs) are a growing class of molecules that...

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PMID: 32533270
DOI: 10.1208/s12248-020-00450-3

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