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Modelling, Extrapolation and Simulation approaches for rare diseases - Review of two case-studies in the INVENTS project

2025-09-17

Abstract excerpt

<h4>A bstract </h4> <h4>Objective</h4> The objective of this work was to review the modelling and simulation methods used in two selected case-studies from the Invents project, with a focus on longitudinal data modelling, simulation methods and extrapolation approaches (across populations, across indications or across similar drugs) applied during the later phases of drug development. <h4>Methods</h4> We includ...

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Literature Corpus work
7666733a-b95b-5755-bf45-287593b9170b
DOI
10.1101/2025.09.17.25335979
Open publication

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Modelling, Extrapolation and Simulation approaches for rare diseases - Review of two case-studies in the INVENTS projectDOI 10.1101/2025.09.17.25335979
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