Article
Deletion of the 5-HT(3A)-receptor subunit blunts the induction of cocaine sensitization.
Genes, brain, and behavior - 1 Feb 2008
Hodge C W, Bratt A M, Kelley S P
Abstract excerpt
Serotonin (5-HT) receptors are classified into seven groups (5-HT(1-7)), comprising at least 14 structurally and pharmacologically distinct receptor subtypes. Pharmacological antagonism of ionotropic 5-HT(3) receptors has been shown to modulate both behavioral and neurochemical aspects of the induction of sensitization to cocaine. It is not known, however, if specific molecular subunits of the 5-HT(3) receptor...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
