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Article

Adaptations in pre- and postsynaptic 5-HT1A receptor function and cocaine supersensitivity in serotonin transporter knockout rats.

Psychopharmacology - 1 Oct 2008

Homberg Judith R, De Boer Sietse F, Raasø Halfdan S, Olivier Jocelien D A, Verheul Mark, Ronken Eric, Cools Alexander R, Ellenbroek Bart A, Schoffelmeer Anton N M, Vanderschuren Louk J M J, De Vries Taco J, Cuppen Edwin

Abstract excerpt

RATIONALE: While individual differences in vulnerability to psychostimulants have been largely attributed to dopaminergic neurotransmission, the role of serotonin is not fully understood. OBJECTIVES: To study the rewarding and motivational properties of cocaine in the serotonin transporter knockout (SERT-/-) rat and the involvement of compensatory changes in 5-HT1A receptor function are the objectives of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18581099
DOI: 10.1007/s00213-008-1212-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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