Article

Prolonged epigenetic and synaptic plasticity alterations following single exposure to a psychedelic in mice

2021-02-25

Abstract excerpt

Clinical evidence suggests a potential therapeutic effect of classic psychedelics for the treatment of depression. The most outstanding and distinct characteristic is the rapid and sustained antidepressant action with one single exposure to the drug. However, the biological substrates and key mediators of psychedelics’ enduring action remain unknown. Here, we show that a single administration of the psychedelic DO...

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Literature Corpus work: e8be12e0-05b4-5f35-ac60-8acf3e1a8a02
DOI: 10.1101/2021.02.24.432725

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