Article
Genetic polymorphisms of phase I metabolizing enzyme genes, their interaction with lifetime grilled and smoked meat intake, and breast cancer incidence.
Annals of epidemiology - 1 Mar 2017
Parada Humberto, Steck Susan E, Cleveland Rebecca J, Teitelbaum Susan L, Neugut Alfred I, Santella Regina M, Gammon Marilie D
Abstract excerpt
PURPOSE: To examine associations between 22 CYP single nucleotide polymorphisms (SNPs) and breast cancer incidence and their interactions with grilled-smoked meat intake, a source of polycyclic aromatic hydrocarbons. METHODS: White women with first primary in situ or invasive breast cancer (n = 988) and frequency-matched controls (n = 1021) from a population-based study were interviewed to assess lifetime...
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