Article
Stochastic phenotypic interconversion in tumors can generate heterogeneity.
European biophysics journal : EBJ - 1 Mar 2017
Simone Giuseppina
Abstract excerpt
Phenotype variations define heterogeneity in biological and molecular systems, and play a crucial mechanistic role, and heterogeneity has been demonstrated in tumor cells. In this work, cells from blood of patients affected by colon cancer were analyzed and sorted using a microfluidic assay based on galactose-active moieties and incubated for culturing in severe combined immunodeficiency (SCID) mice. Based on the...
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