Article
Generalized principles of stochasticity can be used to control dynamic heterogeneity.
Physical biology - 1 Dec 2012
Liao David, Estévez-Salmerón Luis, Tlsty Thea D
Abstract excerpt
It is increasingly appreciated that phenotypic stochasticity plays fundamental roles in biological systems at the cellular level and that a variety of mechanisms generates phenotypic interconversion over a broad range of time scales. The ensuing dynamic heterogeneity can be used to understand biological and clinical processes involving diverse phenotypes in different cell populations. The same principles can be...
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