Article

Transient Commensal Clonal Interactions Can Drive Tumor Metastasis

2020-01-16

Abstract excerpt

To interrogate functional heterogeneity and crosstalk between tumor cells, we generated clonal populations from a patient-derived ovarian clear cell carcinoma model which forms malignant ascites and solid peritoneal tumors upon intraperitoneal transplantation in mice. The clonal populations were engineered with secreted Gaussia luciferase to monitor tumor growth dynamics and tagged with a unique DNA barcode to tr...

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Literature Corpus work: 61520803-98fa-5f6f-a05f-0a79133e9140
DOI: 10.1101/2020.01.16.907071

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