Article
Nonequilibrium population dynamics of phenotype conversion of cancer cells.
PloS one - 1 Jan 2014
Zhou Joseph Xu, Pisco Angela Oliveira, Qian Hong, Huang Sui
Abstract excerpt
Tumorigenesis is a dynamic biological process that involves distinct cancer cell subpopulations proliferating at different rates and interconverting between them. In this paper we proposed a mathematical framework of population dynamics that considers both distinctive growth rates and intercellular transitions between cancer cell populations. Our mathematical framework showed that both growth and transition...
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