Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms of the TGF-β1 gene and the risk of acquired aplastic anemia in a Chinese population.

Annals of hematology - 1 Mar 2017

Liang Xue-Hong, Rong Liucheng, He Guangsheng, He Hailong, Lin Shengyun, Yang Yan, Xue Yao, Fang Yongjun

Abstract excerpt

Acquired aplastic anemia (AA) is a hematological disease characterized by failure of bone marrow hematopoiesis resulting in pancytopenia. While immune-mediated destruction of hematopoietic stem/progenitor cells (HSPCs) plays a central role in the pathophysiology of acquired AA, the transforming growth factor-β1 (TGF-β1) is crucial in adjusting the immune system. The aim of our study was to investigate the role of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Anemia, Aplastic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People

Share to Child, Preschool

Share to Infant

Share to Population Surveillance

Share to Transforming Growth Factor beta1

Source

Open in PubMed Open full text

Identifiers

PMID: 27933374
DOI: 10.1007/s00277-016-2886-5
PMCID: PMC5288442

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms of the TGF-β1 gene and the risk of acquired aplastic anemia in a Chinese population.PMID 27933374Read ↗

The complex pathophysiology of acquired aplastic anaemia.Semantic proximity Read ↗

Immunoregulatory cytokines gene polymorphisms in Egyptian patients affected with acquired aplastic anemia.Semantic proximity Read ↗

The association of cytokine genes polymorphisms and susceptibility to aplastic anemia in Egyptian patients.Semantic proximity Read ↗

Interleukin-10 promoter variability is associated with the susceptibility, severity, and clinical outcomes of aplasitc anemia in Han-Chinese population.Semantic proximity Read ↗

Influence of genetic polymorphisms of IL23R, STAT3, IL12B, and STAT4 on the risk of aplastic anemia and the effect of immunosuppressive therapy.Semantic proximity Read ↗

Common polymorphic deletion of glutathione S-transferase theta predisposes to acquired aplastic anemia: Independent cohort and meta-analysis of 609 patients.Semantic proximity Read ↗

Current Concepts of the Pathogenesis of Aplastic AnemiaSemantic proximity Read ↗

The relationship between interferon-gamma (INF-γ) single nucleotide polymorphism +874(T/A) and occurrence risk of aplastic anemia: a meta-analysis.Semantic proximity Read ↗

Identification of molecular heterogeneity in telomere maintenance pathway of aplastic anemia.Semantic proximity Read ↗

[Acquired aplastic anemia: recent advances in pathophysiology and treatment].Semantic proximity Read ↗

Impact of cytokine gene polymorphisms on risk and treatment outcomes of aplastic anemia.Semantic proximity Read ↗

Causal role of immune cells in aplastic anemia: Mendelian randomization (MR) study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.