Article
Causal role of immune cells in aplastic anemia: Mendelian randomization (MR) study.
Scientific reports - 3 Aug 2024
Fu Shaojie, Du Yazhe, Pan Tingting, Ma Fuzhe, He Hua, Li Yuying
Abstract excerpt
Prior research has identified associations between immune cells and aplastic anaemia (AA); however, the causal relationships between them have not been conclusively established. A two-sample Mendelian randomisation analysis was conducted to investigate the causal link between 731 immune cell signatures and AA risk using publicly available genetic data. Four types of immune signatures, including relative cell,...
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