Article
A systematic review of the role of DNA methylation on inflammatory genes in ulcerative colitis.
Epigenomics - 1 May 2016
Gould Nicholas Jd, Davidson Katharine Lm, Nwokolo Chuka U, Arasaradnam Ramesh P
Abstract excerpt
BACKGROUND: Ulcerative colitis (UC) is an idiopathic disease of the large intestine with evidence pointing to the role of epigenetic changes. METHODS: Searches were performed in three databases (EMBASE, MEDLINE and Web of Science), following PRISMA protocol. DNA methylation was the only epigenetic mechanism affecting genes linked to inflammatory response in UC. RESULTS: A total of 25 differentially methylated...
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