Article
Palmitoleic Acid Improves Metabolic Functions in Fatty Liver by PPARα-Dependent AMPK Activation.
Journal of cellular physiology - 1 Aug 2017
de Souza Camila O, Teixeira Alexandre A S, Biondo Luana A, Lima Junior Edson A, Batatinha Helena A P, Rosa Neto Jose C
Abstract excerpt
BACKGROUND: Palmitoleic acid, since described as lipokine, increases glucose uptake by modulation of 5'AMP-activated protein kinase (AMPK), as well as increasing lipolysis by activation of peroxisome proliferator-activated receptor-α (PPARα), in adipose tissue. However, in liver, the effects of palmitoleic acid on glucose metabolism and the role of PPARα remain unknown. OBJECTIVE: To investigate whether...
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