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Article

Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex.

The Journal of biological chemistry - 8 Mar 2013

Lim Ji-Hong, Gerhart-Hines Zachary, Dominy John E, Lee Yoonjin, Kim Sungjin, Tabata Mitsuhisa, Xiang Yang K, Puigserver Pere

Abstract excerpt

Fatty acids are essential components of the dynamic lipid metabolism in cells. Fatty acids can also signal to intracellular pathways to trigger a broad range of cellular responses. Oleic acid is an abundant monounsaturated omega-9 fatty acid that impinges on different biological processes, but the mechanisms of action are not completely understood. Here, we report that oleic acid stimulates the cAMP/protein...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha

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Source

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Identifiers

PMID: 23329830
DOI: 10.1074/jbc.M112.415729
PMCID: PMC3591621

Genes

SIRT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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