Article

Adiponectin inhibits palmitic acid-induced NLRP3 inflammasome activation in hepatocytes through AMPK-JNK/ErK1/2-NFκB/ROS signaling pathways

2020-03-12

Abstract excerpt

<h4>Background: </h4> Adiponectin, an adipose-derived adipokine, possesses a hepatoprotective role in various liver disorders. Inflammasome activation has been recognized to play a major role during the progression of non-alcoholic fatty liver diseases (NAFLD). However, the effect of adiponectin on NLRP3 inflammasome activation in liver and the exact mechanism remains largely unclear. Here, we assessed the effect...

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Literature Corpus work: b2f82edd-359f-5df8-b735-dc6fd706e681
DOI: 10.21203/rs.3.rs-16972/v1

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