Article

Mammalian Ste20-Like Kinase 1 Regulates AMPK to Mitigate the Progression of Non-Alcoholic Fatty Liver Disease

2024-07-02

Abstract excerpt

<title>Abstract</title> <p>Non-alcoholic steatohepatitis (NASH) escalates adverse liver-related outcomes, with its progression linked to hepatic lipotoxicity induced by excess hepatic free cholesterol (FC) MST1 has been identified as a potential regulator of hepatic lipid metabolism, potentially ameliorating NAFLD. This study aims to delineate the role of MST1 in the progression of NASH. Wild-type (WT) and MST1 g...

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Literature Corpus work: 20c5ed54-45ea-59c2-8003-3d3bf467beea
DOI: 10.21203/rs.3.rs-4443517/v1

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