Article
Examining FKBP5 mRNA expression in human iPSC-derived neural cells.
Psychiatry research - 1 Jan 2017
Lieberman Richard, Kranzler Henry R, Levine Eric S, Covault Jonathan
Abstract excerpt
In peripheral blood leukocytes, FKBP5 mRNA expression is upregulated following glucocorticoid receptor activation. The single nucleotide polymorphism rs1360780 in FKBP5 is associated with psychiatric illness and has functional molecular effects. However, examination of FKBP5 regulation has largely been limited to peripheral cells, which may not reflect regulation in neural cells. We used 27 human induced...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.