Article

Lower cortical <i>FKBP5</i> DNA methylation at key enhancer sites is associated with older age and higher gene expression in schizophrenia

2025-01-31

Abstract excerpt

<h4>ABSTRACT</h4> An increasingly compelling body of literature indicates the glucocorticoid receptor cochaperone FK506-binding protein 51 (FKBP51) is a promising target for novel psychiatric therapeutics. However, the mechanisms regulating the corresponding FKBP5 gene directly in the human brain remain largely unknown yet are needed to facilitate the development of precise mechanism-based treatment approaches....

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Literature Corpus work: f285b5f9-4f7a-5cc6-9403-7c90fc0f44a4
DOI: 10.1101/2025.01.28.635384

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