Article

Differential Dynamics and Roles of FKBP51 Isoforms and Their Implications for Targeted Therapies

2024-08-04

Abstract excerpt

The expression of FKBP5, and its resulting protein FKBP51, is strongly induced by stress and glucocorticoids. Numerous studies have explored their involvement in a plethora of cellular processes and diseases, including psychiatric disorders, inflammatory conditions and cancer. However, there is a lack of knowledge on the role of the different RNA splicing variants and the two protein isoforms that originate from t...

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Literature Corpus work: e2e51b05-c301-58d5-8d56-fa678c9c06ad
DOI: 10.1101/2024.08.03.606475

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