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Article

Longitudinal Characterization of [18F]-FDG and [18F]-AV45 Uptake in the Double Transgenic TASTPM Mouse Model.

Journal of Alzheimer's disease : JAD - 1 Jan 2017

Waldron Ann-Marie, Wyffels Leonie, Verhaeghe Jeroen, Richardson Jill C, Schmidt Mark, Stroobants Sigrid, Langlois Xavier, Staelens Steven

Abstract excerpt

We aimed to monitor the timing of amyloid-β deposition in relation to changes in brain function using in vivo imaging with [18F]-AV45 and [18F]-FDG in a mouse model of Alzheimer's disease. TASTPM transgenic mice and wild-type controls were scanned longitudinally with [18F]-AV45 and [18F]-FDG before (3 months of age) and at multiple time points after the onset of amyloid deposition (6, 9, 12, and 15 months of...

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Identifiers

PMID: 27911309
DOI: 10.3233/JAD-160760
PMCID: PMC5181675

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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