Article
Longitudinal monitoring of sex-related in vivo metabolic changes in the brain of Alzheimer's disease transgenic mouse using magnetic resonance spectroscopy.
Journal of Alzheimer's disease : JAD - 1 Jan 2013
van Duijn Sara, Nabuurs Rob J A, van Duinen Sjoerd G, Natté Remco, van Buchem Mark A, Alia A
Abstract excerpt
Epidemiological studies indicate that the incidence of Alzheimer's disease (AD) is higher in women than in men. There is evidence that changes in metabolites in the brain associated with the development of AD are present earlier than structural brain changes. The effect of sex on the metabolic profile during the development of AD has not yet been studied. In this study we longitudinally monitored and compared in...
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