Article
mutLBSgeneDB: mutated ligand binding site gene DataBase.
Nucleic acids research - 4 Jan 2017
Kim Pora, Zhao Junfei, Lu Pinyi, Zhao Zhongming
Abstract excerpt
Mutations at the ligand binding sites (LBSs) can influence protein structure stability, binding affinity with small molecules, and drug resistance in cancer patients. Our recent analysis revealed that ligand binding residues had a significantly higher mutation rate than other parts of the protein. Here, we built mutLBSgeneDB (mutated Ligand Binding Site gene DataBase) available at...
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