Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

My personal mutanome: a computational genomic medicine platform for searching network perturbing alleles linking genotype to phenotype.

Genome biology - 29 Jan 2021

Zhou Yadi, Zhao Junfei, Fang Jiansong, Martin William, Li Lang, Nussinov Ruth, Chan Timothy A, Eng Charis, Cheng Feixiong

Abstract excerpt

Massive genome sequencing data have inspired new challenges in personalized treatments and facilitated oncological drug discovery. We present a comprehensive database, My Personal Mutanome (MPM), for accelerating the development of precision cancer medicine protocols. MPM contains 490,245 mutations from over 10,800 tumor exomes across 33 cancer types in The Cancer Genome Atlas mapped to 94,563...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Computational Biology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Discovery

Share to Genomics

Share to Neoplasms

Share to Protein Interaction Domains and Motifs

Share to Protein Processing, Post-Translational

Source

Open in PubMed Open full text

Identifiers

PMID: 33514395
DOI: 10.1186/s13059-021-02269-3
PMCID: PMC7845113

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

My personal mutanome: a computational genomic medicine platform for searching network perturbing alleles linking genotype to phenotype.PMID 33514395Read ↗

e-MutPath: Computational modelling reveals the functional landscape of genetic mutations rewiring interactome networksSemantic proximity Read ↗

e-MutPath: computational modeling reveals the functional landscape of genetic mutations rewiring interactome networks.Semantic proximity Read ↗

Structurally-informed human interactome reveals proteome-wide perturbations by disease mutationsSemantic proximity Read ↗

Comprehensive characterization of protein-protein interactions perturbed by disease mutations.Semantic proximity Read ↗

ActiveDriverDB: human disease mutations and genome variation in post-translational modification sites of proteinsSemantic proximity Read ↗

Individualized genetic network analysis reveals new therapeutic vulnerabilities in 6,700 cancer genomes.Semantic proximity Read ↗

ActiveDriverDB: human disease mutations and genome variation in post-translational modification sites of proteins.Semantic proximity Read ↗

A PanorOmic view of personal cancer genomes.Semantic proximity Read ↗

A patient-centric knowledge graph approach to prioritize mutants for selective anti-cancer targetingSemantic proximity Read ↗

Network-aware mutation clustering of cancerSemantic proximity Read ↗

RIPPLET: Mutation-Only Gene and Pathway Profiling for Precision OncologySemantic proximity Read ↗

A structurally informed human protein-protein interactome reveals proteome-wide perturbations caused by disease mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.