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Article

The evolutionary and clinical implications of the uneven distribution of the frequency of the inherited haemoglobin variants over short geographical distances.

British journal of haematology - 1 Feb 2017

Premawardhena Anuja, Allen Angela, Piel Fred, Fisher Chris, Perera Laxman, Rodrigo Rexan, Goonathilaka Gayan, Ramees Lebbe, Peto Tim, Olivieri Nancy, Weatherall David

Abstract excerpt

Studies of the frequency of heterozygous carriers for common inherited diseases of haemoglobin in over 7500 adolescent children in 25 districts in Sri Lanka have disclosed a highly significant variation over very short geographical distances. A further analysis of these findings, including their relationship to the past frequency and distribution of malaria, climatic variation, altitude, ethnic origin and...

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PMID: 27897311
DOI: 10.1111/bjh.14437

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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