Article
G6PD gene variants and its association with malaria in a Sri Lankan population.
Malaria journal - 22 Feb 2015
Dewasurendra Rajika L, Rockett Kirk A, Fernando S Deepika, Carter Richard, Kwiatkowski Dominic P, Karunaweera Nadira D
Abstract excerpt
BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) is an enzyme that plays an important role in many cellular functions. Deficiency of this enzyme results from point mutations in the coding region of the G6PD gene. G6PD-deficiency is important in malaria, as certain anti-malarial drugs could induce haemolysis in such patients and mutations in this gene may influence the susceptibility or resistance to the...
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